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Alethio Therapeutics raises $90M Series A for rare blood cancer antibody

Oxford spinout Alethio Therapeutics secured $90 million in Series A funding to advance an antibody treatment for myeloproliferative neoplasms, a group of rare blood cancers.

Nov 5, 2026·2 sourcesTargeted cancer therapyVenture capital fundingCancer & OncologyBiotech innovationDrug developmentBiotech startupRare diseasesHematology & Blood Cancers
Alethio Therapeutics raises $90M Series A for rare blood cancer antibody
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Hong Kong activist Joshua Wong sentenced to 10 years in prison for collusion

Hong Kong pro-democracy activist Joshua Wong was sentenced to 10 years in prison after pleading guilty to collusion with foreign forces under the national security law, his second conviction under the legislation.

Nov 5, 2026·7 sourcesChina-United States relationsU.S.–China relationsAuthoritarian governanceAuthoritarian governance & repressionCivil liberties & discriminationPolitical imprisonmentWorld affairsHuman rightsHong Kong
Hong Kong activist Joshua Wong sentenced to 10 years in prison for collusion
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Siemens Healthineers begins carve-out of diagnostics business

Siemens Healthineers started carving out its diagnostics business, which it plans to rebrand as Olyrian Diagnostics ahead of a future divestment, and will rebrand the parent company as Healthineers.

Nov 5, 2026·2 sourcesCorporate brandingDiagnostic medicineMergers and acquisitionsMergers & acquisitions (M&A)Corporate strategyCorporate restructuringHealthcare industry
Siemens Healthineers begins carve-out of diagnostics business
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China blocks SoftBank's $5.4 billion acquisition of ABB's robotics division

Chinese regulators have blocked SoftBank Group's deal to acquire ABB's robots unit, according to reports from the Financial Times and other outlets. ABB confirmed it has been informed by SoftBank that Chinese authorities rejected the transaction.

Nov 5, 2026·3 sourcesAI roboticsInternational tradeFinancial tiesWorld affairsOpenAIAI training data
China blocks SoftBank's $5.4 billion acquisition of ABB's robotics division
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South Korea expands anti-piracy operations closer to Strait of Hormuz

South Korea announced plans to expand its Cheonghae anti-piracy unit operations to waters closer to the Strait of Hormuz, following US pressure, and will deploy maritime patrol aircraft and explosive ordnance disposal teams to help keep the waterway open.

Nov 5, 2026·7 sourcesNaval operationsIran WarHormuz closure & shippingStrait of HormuzMine clearance in Strait of HormuzMaritime securityStrait of Hormuz blockageU.S. Iran war
South Korea expands anti-piracy operations closer to Strait of Hormuz
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Hong Kong activist Joshua Wong to be sentenced on national security collusion charge

Prominent pro-democracy activist Joshua Wong faces sentencing in Hong Kong for collusion with foreign entities under the Beijing-imposed national security law, which carries a maximum penalty of life imprisonment. This marks his second conviction under the law.

Nov 4, 2026·4 sourcesProtests and civil unrestHong KongAuthoritarian governance & repressionMarco RubioPolitical imprisonmentHuman rightsAuthoritarian governance
Hong Kong activist Joshua Wong to be sentenced on national security collusion charge
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Goldman Sachs and Apollo seek buyers for SpaceX's $40 billion AI chip financing deal

Goldman Sachs and Apollo Global Management are in talks with investors to sell portions of a roughly $40 billion chip financing deal for SpaceX, as the AI boom continues to drive massive infrastructure investments.

Nov 4, 2026·2 sourcesCongressAI investmentAI chipsAI bubbleTexasAI bubble concernsNVIDIA GPUAI data centersCompute, chips & AI infrastructure
Goldman Sachs and Apollo seek buyers for SpaceX's $40 billion AI chip financing deal
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Ricursive releases Ripple-65B Preview open-weight coding model

Ricursive Intelligence released Ripple-65B Preview, a 65-billion parameter dense open-weight model pretrained from scratch for agentic coding. The model scores 80.5 on Terminal-Bench 2.1 and is available under Apache 2.0 license.

Nov 4, 2026·2 sourcesAI benchmarksPre-trainingMetaNvidia RTX SparkReinforcement LearningSWE-Bench VerifiedAI ModelsAI codingCoding agentsAI agentsOpen-weight models
Ricursive releases Ripple-65B Preview open-weight coding model
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AstraZeneca made $10 billion offer for obesity drugmaker Rhythm Pharmaceuticals

AstraZeneca made a $10 billion takeover offer for Rhythm Pharmaceuticals, which specializes in treatments for metabolic conditions and severe obesity, according to sources familiar with the matter.

Nov 4, 2026·2 sourcesEli LillyNovo NordiskRare diseasesObesity treatmentPharmaceutical IndustryMergers & acquisitions (M&A)Weight loss drugsMergers and acquisitionsCorporate strategy
AstraZeneca made $10 billion offer for obesity drugmaker Rhythm Pharmaceuticals
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Saudi Arabia and Syria sign defense cooperation agreement

Saudi Arabia and Syria signed a defense cooperation agreement as Yemen's Houthi attacks escalate, marking a significant step in normalizing relations between Riyadh and Damascus after years of estrangement.

Nov 4, 2026·3 sourcesWorld affairsSyrian post-conflict recoveryGulf statesHouthi drone attacks on Saudi ArabiaSyriaDefense alliancesDiplomacyRegional security
Saudi Arabia and Syria sign defense cooperation agreement
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Former FBI agent Patrick Yaroch to plead guilty to stealing $1 million in crypto

Former FBI supervisory special agent Patrick Steven Yaroch is set to plead guilty to stealing approximately $1 million in cryptocurrency using access to counterintelligence case files. Prosecutors said Yaroch used ChatGPT to plan a move to Portugal.

Nov 4, 2026·2 sourcesFederal agenciesCrypto enforcement actionsJudiciary
Former FBI agent Patrick Yaroch to plead guilty to stealing $1 million in crypto
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Zcash NU7 upgrade to freeze $16 million in oldest privacy pool

The NU7 network upgrade will disable the transaction type needed to spend from Sprout, leaving roughly 12,226 ZEC stranded unless holders migrate before the upgrade expected around November 5.

Nov 4, 2026·2 sourcesCryptocurrenciesPrivacy coinsZcashSelf-custodyAltcoins
Zcash NU7 upgrade to freeze $16 million in oldest privacy pool
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Meta acquires Conductor AI coding startup for multi-agent management

Meta has acquired Conductor, an AI coding startup that enables software engineers to manage multiple coding agents simultaneously. The deal shows Meta's ambition to own coding infrastructure as AI agents become more prevalent.

Nov 4, 2026·3 sourcesAI startupsCoding agentsAI developer toolsOpenAIMeta Superintelligence LabsMoltbookAI codingMetaClaude CodeMulti-agent orchestrationAI IndustryAI agents
Meta acquires Conductor AI coding startup for multi-agent management
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US sanctions Indian and Turkish firms for aiding Iran's oil trade

The US Treasury imposed sanctions on companies and individuals in India and Turkey for supporting Iran's oil sales and shadow fleet operations, targeting what officials called a 'vast criminal network' helping Tehran fund its activities.

Nov 4, 2026·3 sourcesUS blockade's impact on Iranian oil exportsU.S. sanctions on Iranian airlinesEconomic SanctionsScott BessentUS midterm electionsIran sanctionsTrump administrationIran War2026 U.S. midterm elections
US sanctions Indian and Turkish firms for aiding Iran's oil trade
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Polygon proposes hard fork to recover $6.8 million in stolen Binance and Polymarket funds

A governance proposal would zero out five attacker-controlled addresses and send roughly 70.49 million POL back to verified recovery accounts. Polygon block producers have already frozen the stolen tokens.

Nov 4, 2026·4 sourcesCrypto securityBlockchain governanceCrypto hacksBinance hot-wallet breach
Polygon proposes hard fork to recover $6.8 million in stolen Binance and Polymarket funds
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Schroders launches tokenized bond fund on Solana

Asset manager Schroders launched a tokenized emerging markets debt fund on Solana through Centrifuge, marking the $1.1 trillion firm's first deployment on the network.

Nov 4, 2026·2 sourcesTokenizationInstitutional crypto adoptionSolanaTokenized securities
Schroders launches tokenized bond fund on Solana
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OpenAI acquires Pierre Computer Company to integrate code storage into Codex

OpenAI is acquiring Pierre Computer Company, the startup behind Code Storage and other developer tools already integrated into Codex. The deal aims to help Codex better connect code across repositories and improve AI coding workflows.

Nov 4, 2026·4 sourcesAI developer toolsAI codingAI startupsCoding agentsCodex (AI system)AI IndustryOpenAIMicrosoft
OpenAI acquires Pierre Computer Company to integrate code storage into Codex
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JD Vance blames Iran war for Republican midterm election losses

US Vice President JD Vance publicly broke with President Trump, attributing the Republican Party's sweeping defeat in the 2026 midterm elections to voter anger over the Iran war and rising oil prices. Trump later acknowledged the war "largely" contributed to GOP losses but defended the military campaign as necessary.

Nov 4, 2026·7 sourcesUS SenatePolitical partiesIran WarDemocratic PartyPete Hegseth2026 U.S. midterm electionsSenate racesJD VanceEnergyTrump administrationRepublican PartyCongressElectionsUS midterm electionsU.S. House of Representatives
JD Vance blames Iran war for Republican midterm election losses
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Sentra raises $150 million Series C to secure AI agent data access

Data security startup Sentra raised $150 million in Series C funding led by Capital One Ventures to expand its platform that controls what AI agents can access in corporate data systems.

Nov 4, 2026·3 sourcesAI startupsAI agentsAI securityUnit 8200AI governanceAgent permissionsVenture capital fundingAI cybersecurity
Sentra raises $150 million Series C to secure AI agent data access
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UK Supreme Court hears Palestine Action challenge to terrorism ban

Palestine Action co-founder contested Britain's designation of the activist group as a terrorist organization at the UK Supreme Court, with police arresting over two dozen supporters outside the hearing.

Nov 4, 2026·5 sourcesIsrael-Palestine ConflictIsrael-Gaza warHamasTerrorismHuman rightsProtest policingCivil liberties & discriminationProtests and civil unrest
UK Supreme Court hears Palestine Action challenge to terrorism ban
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Ethiopia expels six Sudanese diplomats amid allegations of RSF support

Ethiopia ordered six Sudanese consular staff to leave the country and closed Sudan's consulate in Assosa, marking further deterioration in relations over allegations that Khartoum supports the Rapid Support Forces.

Nov 4, 2026·6 sourcesEthiopia's expulsion of Sudanese consular staffRenewed Tigray war - September 2026 offensiveEthiopia–Eritrea diplomatic ruptureWars & conflictsForeign intervention in Sudan's warDiplomacySudan civil warEthiopia's internal conflictsAttacks on Sudan's electricity grid
Ethiopia expels six Sudanese diplomats amid allegations of RSF support
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Iranian officials celebrate US midterm results as rebuke of Trump's war

Iranian government officials publicly welcomed the Democratic victories in US midterm elections, interpreting the results as American voters rejecting President Trump's military actions against Iran. The response came as Tehran remained on high alert amid ongoing conflict.

Nov 4, 2026·4 sourcesCongressIslamic Revolutionary Guard CorpsStrait of Hormuz blockage2026 U.S. midterm electionsThe U.S.-Iran war: parties, proxies & operationsIran WarUS strikes on Qeshm IslandRepublican PartyQatar mediationElectionsFinancial tiesDemocratic PartyUS midterm electionsTrump administrationStrait of Hormuz
Iranian officials celebrate US midterm results as rebuke of Trump's war
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Circle cuts 5% of workforce despite profitable third quarter

USDC issuer Circle disclosed a roughly 5% workforce reduction in a footnote to Q3 earnings that showed revenue up 17% to $865 million and net income of $226 million, without specifying the number of employees affected.

Nov 4, 2026·3 sourcesStablecoinsCircle Arc mainnet launch
Circle cuts 5% of workforce despite profitable third quarter
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Cyberattack targets French blood banks and Credit Mutuel Arkea bank

Multiple cyberattacks hit French infrastructure on November 2-4, targeting blood bank refrigeration systems at three sites and enabling fraudulent transactions at Credit Mutuel Arkea bank totaling approximately €118 million ($112 million). The blood bank attack attempted to raise storage temperatures but was thwarted by alarm systems before damaging products.

Nov 4, 2026·2 sourcesCybersecurityHealthcare cybersecurityBlood safetyCyber warfareCritical infrastructure security
Cyberattack targets French blood banks and Credit Mutuel Arkea bank
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Iran exempts vessels from India, Iraq, Qatar and China from Strait of Hormuz restrictions

Iran announced exemptions for ships from four countries from transit restrictions in the Strait of Hormuz, citing mutual interests and specific trade relationships including medicine imports from India.

Nov 4, 2026·3 sourcesIran WarEnergyStrait of Hormuz blockageUS strikes on Qeshm IslandOil prices & energy marketsHormuz closure & shippingIran's country-specific exemptions from Hormuz transit restrictions2026 U.S. midterm electionsStrait of Hormuz energy crisisMaritime feesStrait of Hormuz
Iran exempts vessels from India, Iraq, Qatar and China from Strait of Hormuz restrictions
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Hong Kong passes OECD crypto tax reporting rules effective January 2027

Hong Kong's Legislative Council passed legislation implementing OECD crypto tax reporting standards, requiring exchanges and brokers with Hong Kong ties to collect user transaction data for tax authorities starting January 1, 2027.

Nov 4, 2026·2 sourcesHong KongCrypto exchangesCrypto regulationCrypto taxationCompliance
Hong Kong passes OECD crypto tax reporting rules effective January 2027
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Aaron Ford becomes Nevada's first Black governor

Democrat Aaron Ford, Nevada's attorney general, defeated Republican incumbent Joe Lombardo to become the state's first Black governor.

Nov 4, 2026·4 sources2026 U.S. midterm electionsU.S. election resultsElectionsRepublican PartyDemocratic PartyRace & ethnicityU.S. governorsUS midterm electionsState politics
Aaron Ford becomes Nevada's first Black governor
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Morgan Stanley among first banks using DTCC tokenization service

Morgan Stanley began using the Depository Trust & Clearing Corporation's new tokenization infrastructure to tokenize US equities and Treasuries, joining initial users of the service that launched October 28.

Nov 4, 2026·2 sourcesTokenized equitiesInstitutional crypto adoptionTokenized securitiesTokenizationDTCC (Depository Trust & Clearing Corporation)
Morgan Stanley among first banks using DTCC tokenization service
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Google announces $15 billion investment in Malaysia data centers over two years

Alphabet's Google will invest $15 billion to expand data center and cloud operations in Malaysia, building new campuses in Selangor and Negeri Sembilan states to support AI infrastructure demand.

Nov 4, 2026·2 sourcesCloud ComputingAI data centersAI investmentAlphabet Inc.Compute, chips & AI infrastructureArtificial intelligence infrastructureAI Data Center Gold RushAlphabet
Google announces $15 billion investment in Malaysia data centers over two years
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Sino Biopharmaceutical signs cancer deal worth up to $7 billion with Boehringer Ingelheim

Sino Biopharmaceutical entered an option and license agreement with Germany's Boehringer Ingelheim for six pre-clinical oncology programs that could generate up to approximately $7 billion in total value.

Nov 4, 2026·3 sourcesDrug developmentHong KongCancer immunotherapyTargeted cancer chemotherapyPharmaceutical IndustryCancer & Oncology
Sino Biopharmaceutical signs cancer deal worth up to $7 billion with Boehringer Ingelheim
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Novo Nordisk raises 2026 outlook for third time on strong Wegovy pill sales

Novo Nordisk raised its full-year forecast for the third time in 2026 after third-quarter sales of its Wegovy weight-loss pill reached $807 million, beating analyst expectations and driving stronger-than-expected quarterly earnings.

Nov 4, 2026·4 sourcesNovo NordiskEli LillyPrescription drug costsWeight loss medications & GLP-1 drugsPharmaceutical earningsZepboundPharmaceutical IndustryDrug Policy, Pricing & ApprovalLifestyle, Wellness and NutritionFoundao
Novo Nordisk raises 2026 outlook for third time on strong Wegovy pill sales
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Democrats win control of both chambers of Congress in midterm elections

Democrats seized control of the Senate and House of Representatives in the 2026 midterm elections, delivering a sweeping rebuke to President Trump and the Republican Party. Trump and Vice President Vance acknowledged the Iran war played a significant role in the losses.

Nov 4, 2026·5 sourcesStrait of HormuzPolitical partiesSenate racesRepublican PartyU.S. House of RepresentativesCongressDemocratic PartyTrump administrationElectionsUS Senate2026 U.S. midterm electionsUS midterm electionsJD Vance
Democrats win control of both chambers of Congress in midterm elections
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Tencent releases Hy4 AI model, claims top-tier status among Chinese open-source systems

Tencent released Hy4, a new foundation AI model that the company says joins the top tier of Chinese open-weight AI systems, with built-in limits intended to reduce cybersecurity and harmful biological research risks.

Nov 4, 2026·3 sourcesOpen-weight modelsAI cybersecurityTencent-linked AI agents probing Alibaba's AmapChinese AI modelsAI ModelsAI SafetyAI agentsFrontier modelsOpenAI
Tencent releases Hy4 AI model, claims top-tier status among Chinese open-source systems
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Oracle cancels $7 billion Tencent AI chip deal under Trump pressure

Oracle Corp. has canceled a $7 billion chip leasing deal with Tencent Holdings after pressure from the Trump administration, according to the Financial Times.

Nov 4, 2026·3 sourcesFinancial tiesU.S. technology trade restrictionsCompute access and pricingChip export controlsAI chipsUS–China AI competitionAI data centersTrump administrationCompute, chips & AI infrastructure
Oracle cancels $7 billion Tencent AI chip deal under Trump pressure
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BitMart confirms hack during wind-down, linked to Mercado Bitcoin attack

BitMart founder Sheldon Xia confirmed a security breach affecting the exchange during its ongoing wind-down and restructuring, with onchain analysis reportedly tying the incident to the larger Mercado Bitcoin attack.

Nov 4, 2026·3 sourcesCrypto exchangesCrypto hacksCentralized exchange hackExchange & custodial failuresCrypto security
BitMart confirms hack during wind-down, linked to Mercado Bitcoin attack
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Democrats flip multiple state legislatures and governorships

Democrats gained control of state legislatures in Wisconsin, Minnesota, Michigan, Pennsylvania, and North Carolina, while winning governorships in at least five states previously held by Republicans, including Nevada and Ohio.

Nov 4, 2026·4 sourcesDemocratic PartyU.S. governors2026 U.S. midterm electionsState politicsU.S. election resultsUS midterm electionsTexasElectionsPolitical partiesRepublican Party
Democrats flip multiple state legislatures and governorships
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Democrats flip Iowa Senate seat as Josh Turek defeats Ashley Hinson

Democrat Josh Turek, a state representative and former wheelchair basketball star, defeated Republican Rep. Ashley Hinson in Iowa's U.S. Senate race, flipping a Republican-held seat and marking Iowa's first Democratic senator in more than a decade.

Nov 4, 2026·4 sourcesUS midterm electionsUS SenateU.S. election resultsRepublican PartyElectionsJosh Turek flips Iowa’s open Senate seatU.S. Senate politicsSenate racesU.S. swing states & battlegroundsNew York TimesU.S. House of Representatives2026 U.S. midterm electionsDemocratic Party
Democrats flip Iowa Senate seat as Josh Turek defeats Ashley Hinson
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Maryland voters approve Democratic-backed redistricting amendment

Maryland voters approved a constitutional amendment that allows Democrats to redraw the state's congressional map mid-decade, ensuring the redistricting battle continues.

Nov 4, 2026·3 sourcesGerrymanderingDemocratic PartyElectionsTexasUS midterm elections2026 U.S. midterm electionsU.S. election resultsPolitical partiesU.S. House of RepresentativesState politicsNiall FergusonU.S. redistricting & gerrymandering
Maryland voters approve Democratic-backed redistricting amendment
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Byron Donalds becomes Florida's first Black governor

Republican Rep. Byron Donalds defeated Democrat David Jolly to become Florida's next governor and the state's first Black leader, in one of the country's most-watched midterm races.

Nov 4, 2026·3 sourcesState politicsBill ClintonAI data center political backlashDemocratic Party2026 U.S. midterm electionsRepublican PartyUS midterm electionsElectionsU.S. governorsHousing affordability
Byron Donalds becomes Florida's first Black governor
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Keisha Lance Bottoms becomes first Black woman elected governor in US

Democrat Keisha Lance Bottoms, former Atlanta mayor, won Georgia's gubernatorial race, becoming the first Black woman elected governor in US history and flipping the state from Republican control.

Nov 4, 2026·7 sourcesElectionsSenate racesUS midterm electionsRepublican Party2026 U.S. midterm electionsDemocratic PartyU.S. governorsKeisha Lance Bottoms wins Georgia governor’s racePolitical partiesJoe BidenState politicsU.S. election results
Keisha Lance Bottoms becomes first Black woman elected governor in US
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