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Novartis reveals cancer cases possibly linked to gene therapy Zolgensma

BioPharma DiveView source article

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Novartis links two tumor cases in children to Zolgensma gene therapy

Novartis disclosed that two of nine reported tumor cases in Zolgensma recipients showed evidence of the viral delivery vector integrating into patient DNA, raising new safety questions for the gene therapy field.

Nov 6, 2026·3 sourcesCancer & OncologyPharmaceutical IndustryGene therapyDrug safetyGenetic diseasesPost-market surveillance
Novartis links two tumor cases in children to Zolgensma gene therapy
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Other sources for this story

Reuters

Two tumour cases in children linked to SMA drug, Novartis says | Reuters

STAT News

Zolgensma tumor cases show risks of a common gene therapy tool