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Novartis, Bristol Myers pause autoimmune CAR-T trials due to safety concerns

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Novartis and Bristol Myers pause autoimmune CAR-T trials due to safety concerns

Novartis has halted development of rap-cel in multiple indications and Bristol Myers voluntarily paused enrollment in autoimmune CAR-T trials after observing safety issues in testing.

Aug 31, 2026·2 sourcesAutoimmune disease treatmentImmunotherapyDrug development
Novartis and Bristol Myers pause autoimmune CAR-T trials due to safety concerns
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Endpoints

Three deaths in CAR-T trials prompt halt by Novartis; Bristol Myers programs also paused

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