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An ‘off-the-shelf’ CAR-T therapy from Adicet shows promise against lupus

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Adicet Bio's off-the-shelf CAR-T therapy shows promise in lupus trial

Adicet Bio reported positive early trial results for prula-cel, an off-the-shelf gamma delta CAR-T therapy for systemic lupus erythematosus. At 12 months, 54% of evaluable patients achieved DORIS remission with no severe side effects, surpassing benchmarks set by personalized CAR-T treatments.

Sep 28, 2026·4 sourcesImmunotherapyCAR T-cell therapyClinical trialsBiotechnologyAutoimmune disease treatment
Adicet Bio's off-the-shelf CAR-T therapy shows promise in lupus trial
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Adicet Bio Announces Positive Safety and Efficacy Data from Prula-cel (formerly ADI-001) Study in Patients with Systemic Lupus Erythematosus with or without Lupus Nephritis