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Verdiva ends mid-stage study of oral GLP-1 amid ‘market evolution’

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Verdiva Bio discontinues Phase 2 trial of oral GLP-1 drug VRB-101 for obesity maintenance

Verdiva Bio has terminated its Phase 2 study testing VRB-101, an oral formulation of the GLP-1 drug ecnoglutide, as a maintenance treatment for patients with overweight and obesity. The company cited 'market evolution' as the reason for the business decision, which was not based on safety concerns, though it will continue developing the drug for other weight loss indications.

Oct 14, 2026·2 sourcesWeight management
Verdiva Bio discontinues Phase 2 trial of oral GLP-1 drug VRB-101 for obesity maintenance
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Verdiva cans mid-stage obesity trial of GLP-1 pill, citing 'market evolution'