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'Molecular glue' stabilizes protein that inhibits development of non–small cell lung cancer and uterine cancer

MedicalxpressView source article

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Molecular glue RPT04402 stabilizes PP2A protein to inhibit lung and uterine cancer development

Researchers have developed RPT04402, a molecular glue that stabilizes protein phosphatase 2A (PP2A), a key regulator of cell signaling pathways frequently disrupted in tumors. The compound shows promise in inhibiting non-small cell lung cancer and uterine cancer development.

Oct 22, 2026·3 sourcesCancer & OncologyBiomedical researchCancer researchDrug discoveryCancer treatmentTargeted cancer therapyDrug developmentMolecular biology
Molecular glue RPT04402 stabilizes PP2A protein to inhibit lung and uterine cancer development
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