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Tegoprubart preserves kidney function better than tacrolimus in first-time transplant patients, trial suggests

MedicalxpressView source article

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Tegoprubart outperforms tacrolimus in preserving kidney function after transplant, BESTOW trial finds

The Phase 2 BESTOW clinical trial demonstrated that tegoprubart, a novel anti-CD40L antibody therapy, was superior to tacrolimus, the current standard of care, at preserving kidney function in adults receiving their first kidney transplant. The trial results suggest a potential advancement in immunosuppressive treatment regimens for transplant patients.

Oct 23, 2026·3 sourcesClinical trialsImmunologyOrgan transplantationDrug developmentRandomized controlled trialRenal systemBiotech innovation
Tegoprubart outperforms tacrolimus in preserving kidney function after transplant, BESTOW trial finds
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