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Population-scale reconstruction of menopause dynamics reveals a physiological cliff at the final menstrual period - Nature Medicine

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Study finds menopause marks abrupt physiological shift across multiple body systems

A new study published in Nature Medicine reveals that the final menstrual period represents a sudden, cliff-like biological transition affecting multiple body systems, with sex hormone changes beginning more than 10 years before menopause onset. The research, based on laboratory data from two independent cohorts, challenges the common assumption that menopause is a gradual process.

Oct 12, 2026·4 sourcesAging (Biology)Women’s health
Study finds menopause marks abrupt physiological shift across multiple body systems
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