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Experimental Lilly combination drug tops Zepbound in weight-loss trial | Reuters

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Eli Lilly's amylin-Zepbound combination shows record 23% weight loss in diabetes trial

Eli Lilly reported that its experimental combination of amylin drug eloraTZP with Zepbound (tirzepatide) achieved up to 23% weight loss in patients with type 2 diabetes and obesity, outperforming Zepbound alone and representing the highest weight loss seen in similar studies to date.

Sep 30, 2026·6 sourcesZepboundEli LillyWeight managementClinical trialsDrug developmentMetabolic health
Eli Lilly's amylin-Zepbound combination shows record 23% weight loss in diabetes trial
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Lilly's amylin-Zepbound combo posts best-ever weight loss in patients with obesity and diabetes

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Eli Lilly says closely watched combo obesity regimen boosts weight loss in mid-stage trial

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Diabetes Patients Lose Up to 54 Pounds With New Drug Combination, Eli Lily Says

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Lilly’s Next-Gen Obesity Drug Helps People Lose Even More Weight in Study

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Eli Lilly’s Zepbound combined with amylin drug led to significant weight loss in mid-stage trial