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Chronic obstructive pulmonary disease stories

Sep 8, 2026

AstraZeneca's experimental COPD drug significantly reduces flare-ups in late-stage trials

AstraZeneca's experimental drug for chronic obstructive pulmonary disease significantly reduced dangerous flare-ups across a wide range of patients in two late-stage trials, positioning it as a potential blockbuster treatment for the deadly lung condition.

Sep 8, 2026·3 sources
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Top claims

  • ▪AstraZeneca's tozorakimab is currently under priority review by the U.S. Food and Drug Administration, with regulatory approval expected in the first quarter of 2027
  • ▪AstraZeneca CEO Pascal Soriot noted that previous industry attempts to target the IL-33 protein had limited success, leading to low initial investor expectations for tozorakimab
  • ▪AstraZeneca's tozorakimab reduced moderate and severe COPD flare-ups by approximately 30% across the overall trial population of current and former smokers over one year

Topics

Respiratory diseasesClinical trials