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Medicines and Healthcare products Regulatory Agency stories

Oct 15, 2026

UK antidepressant labels to add boxed warnings on suicide risk and sexual dysfunction

The UK Medicines and Healthcare products Regulatory Agency will strengthen antidepressant safety warnings with boxed alerts on suicidal thoughts and behaviors and sexual dysfunction, with patient cards expected in medicine packs.

Oct 15, 2026·2 sources
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Top claims

  • ▪The UK Medicines and Healthcare products Regulatory Agency announced updated safety warnings for all 28 authorised antidepressants, introducing boxed warnings on suicidal thoughts and behaviours in patient information leaflets
  • ▪The Commission on Human Medicines review into antidepressant safety was initiated after patients and families raised concerns regarding the communication of suicidal thoughts and persistent sexual dysfunction risks
  • ▪The MHRA said Antidepressant leaflet wording will be amended to remove references to a chemical imbalance and describe drug function in line with current clinical understanding

Topics

Patient safetySuicide preventionMental healthDepression

Related entities

United Kingdom