University of California, San Francisco (UCSF) stories

Stanford and UCSF researchers discover tau protein infiltrates mitochondria, disrupting energy production in Alzheimer's disease

Scientists at Stanford University School of Medicine and University of California, San Francisco have identified a novel toxic mechanism in which hyperphosphorylated tau protein enters nerve cell mitochondria and reverses electron flow, potentially driving Alzheimer's disease and other neurodegenerative tauopathies.