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Aug 4, 2026

Pathos AI Signs Two Major Breast Cancer Drug Licensing Deals Worth Over $2B, Plans $3B Series E

Pathos AI announced two significant licensing agreements for breast cancer treatments: a $2.2 billion deal with China's Alphamab Oncology for bispecific ADC JSKN016 targeting triple-negative breast cancer, and a co-exclusive agreement with AstraZeneca for ERα degrader AZD4241 for ER-positive breast cancer. The company is reportedly planning to raise a Series E round at a $3 billion valuation.

Aug 4, 2026·8 sources
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Top claims

  • ▪Under the licensing agreement, Alphamab Oncology will receive a non-refundable upfront payment of $125 million from Pathos AI.
  • ▪JSKN016 is conjugated via site-specific glycosylation to achieve a stable drug-to-antibody ratio of 4.
  • ▪The addition of JSKN016 expands Pathos AI's clinical pipeline to four assets, including pocenbrodib, DO-2, and AZD4241.

Topics

AI in drug discoveryVenture capital fundingOncology