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May 12, 2026

Astellas Returns to Gene Therapy for Rare Disease XLMTM After Previous Trial Disaster

Five years after a disastrous trial where some boys died while others had astonishing recoveries, Astellas is returning with a revised gene therapy treatment for X-linked myotubular myopathy (XLMTM), offering new hope to a devastated rare disease community.

May 12, 2026·2 sources
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Top claims

  • ▪Astellas' XLMTM gene therapy program was described as a resurrected effort in a once-devastated rare disease program.
  • ▪Alzheimer's drug adoption was underwhelming as of May 11, 2026.
  • ▪Jessica Gonzalez noticed that an hour had elapsed without suctioning Joshua Jacob Gonzalez after treatment at the National Institutes of Health, whereas previously missing one suction could cause Joshua Jacob Gonzalez's airways to clog and he could die.

Topics

Gene therapyClinical trials

Related entities

Rare DiseaseGeriatric medicine

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