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Immunosuppression stories

Apr 17, 2026

First-in-Human Trial Shows Liver Transplant Patients Can Stop Immunosuppressants After Cell Therapy

UPMC and University of Pittsburgh researchers successfully weaned multiple liver transplant patients off all immunosuppressant drugs for over three years using a pre-transplant cell therapy approach, representing a potential breakthrough in organ transplantation.

Apr 17, 2026·2 sources
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Top claims

  • ▪The pre-transplant cell therapy approach developed by UPMC and University of Pittsburgh could end the need for lifelong anti-rejection drugs.
  • ▪The UPMC and University of Pittsburgh study specifically required living donors rather than deceased donors to obtain the necessary cells.
  • ▪Liver transplants replace livers damaged by alcohol-associated liver disease, metabolic-associated liver disease, liver cancer, or other causes.

Topics

Clinical trialsRegenerative medicineOrgan transplantation

Related entities

Liver disease

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