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Sep 14, 2026

Definium's LSD-based drug succeeds in third Phase 3 anxiety trial

Definium Therapeutics reported that its oral LSD-based treatment DT120 reduced symptoms of generalized anxiety disorder in a second successful late-stage study, marking the company's third Phase 3 win this year for the candidate.

Sep 14, 2026·2 sources
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Aug 12, 2026

Definium reports positive Phase 3 results for single-dose DT120 in generalized anxiety disorder

Definium Therapeutics announced its experimental LSD-based pill significantly reduced anxiety symptoms in a late-stage study, meeting the trial's main goal. The results mark the company's second major win in two months and sent shares up more than 20% in premarket trading.

Aug 12, 2026·2 sources
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Jun 22, 2026

Definium's LSD-Based Pill Reduces Depression Symptoms in Late-Stage Trial

Definium Therapeutics reported that a single dose of its LSD-based experimental pill significantly reduced symptoms of major depression in patients in a late-stage trial, sending shares higher. The data brings the drug closer to potential FDA approval.

Jun 22, 2026·2 sources
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Top claims

  • ▪The FDA should approve Definium's LSD-based drug DT120
  • ▪The September 14, 2026 readout represents Definium Therapeutics' third successful Phase 3 trial for DT120 in 2026, following an anxiety trial in August 2026 and a depression trial in June 2026
  • ▪Definium Therapeutics added a 50-microgram dose arm to its DT120 clinical trial of 245 patients to address functional unblinding

Subtopics

Drug Approval and Clinical Trials3Psychedelic clinical research & trials3Psychedelic policy & regulation3Anxiety2Mental health2Depression1Mental health1Psychedelic assisted therapy1Psychedelic renaissance1Psychedelics for depression1

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