Systematic reviews stories

Sep 17, 2026

Systemic lupus erythematosus linked to increased risk for stroke

A systematic review found that systemic lupus erythematosus (SLE) is associated with an increased risk for stroke, including both ischemic and hemorrhagic stroke types.

Sep 17, 20261 source

Apr 16, 2026

Anti-Amyloid Alzheimer's Drugs Show No Clinically Meaningful Benefit in Cochrane Review

A new Cochrane review found that drugs targeting amyloid beta proteins in the brain likely have no clinically meaningful positive effects while increasing the risk of brain bleeding and swelling.

Apr 16, 20261 source

Top claims

▪The meta-analysis found that patients with systemic lupus erythematosus had a significantly increased risk for any stroke, with a pooled risk ratio of 2.60.
▪Most cohort studies in the systemic lupus erythematosus meta-analysis adjusted for major cardiovascular risk factors, though the authors noted that residual confounding may have persisted.
▪The authors of the *Lupus Science & Medicine* study concluded that systemic lupus erythematosus represents an independent and substantial risk factor for all stroke subtypes.

Subtopics

Alzheimer’s & dementia1 Autoimmune disease1 Biomarkers & bloodwork testing1 Cardiovascular health.1 Drug Approval and Clinical Trials1 Medical research1 Mental health1

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