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Cholesterol management stories

Jul 21, 2026

Nearly All US Heart Disease Deaths Linked to Modifiable Risk Factors, New Research Shows

A new study published in JAMA Cardiology reveals that approximately 90% of ischemic heart disease deaths in the United States remain attributable to modifiable risk factors including blood pressure, diet, and LDL cholesterol, despite significant declines in mortality since 1990. Research also shows these factors are linked to unstable coronary artery plaques that lead to heart attacks.

Jul 21, 2026·4 sources
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Jul 16, 2026

Merck wins FDA approval for first oral PCSK9 cholesterol pill

Merck received FDA approval for its oral PCSK9 inhibitor cholesterol pill, the first of its kind, offering a more convenient alternative to existing injectable therapies for high-risk patients.

Jul 16, 2026·4 sources
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May 25, 2026

Eli Lilly's Gene-Editing Therapy Reduces Cholesterol by 62% in Early Clinical Trial

Eli Lilly reported that a high dose of its gene-editing therapy from Verve Therapeutics reduced cholesterol levels by 62% in participants in an early-stage clinical trial, representing a significant advance in gene-editing treatments for cardiovascular disease.

May 25, 2026·1 source
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Top claims

  • ▪High systolic blood pressure accounted for approximately 47.2% of ischemic heart disease deaths in the United States in 2023.
  • ▪From 1990 to 2023, United States ischemic heart disease deaths attributable to high fasting plasma glucose rose from 12.9% to 18%, representing a 10.5% increase.
  • ▪Dietary risks accounted for approximately 38.6% of United States ischemic heart disease deaths in 2023, while high LDL cholesterol accounted for 28.5%.

Subtopics

Drug Approval and Clinical Trials3Pharma2Blood pressure management1Cardiovascular health1Cardiovascular health.1Clinical trials1Eli Lilly1FDA drug approval1Preventive medicine1Public health research1

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