Clinical decision support stories

Sep 13, 2026

Multimodal AI model outperforms established biomarkers for immunotherapy in lung cancer

A large international real-world study found that a multimodal explainable AI decision support tool outperformed established biomarkers for predicting immunotherapy outcomes in non-small cell lung cancer and improved physician decision-making.

Sep 13, 20262 sources

Apr 30, 2026

OpenAI Model Surpasses Physicians on Clinical Reasoning Tasks in Large-Scale Study

Researchers published in Science results showing an OpenAI artificial intelligence model outperformed physicians on diagnostic and clinical reasoning tasks, including real emergency department data, in one of the largest AI-physician comparison studies to date.

Apr 30, 20262 sources

Top claims

▪The agreement on disease control rate predictions between expert and nonexpert physicians improved from slight (kappa of 0.11) to moderate (kappa of 0.48) when using the I3LUNG artificial intelligence tool
▪The I3LUNG study integrated four distinct patient data modalities: clinical and blood data, computed tomography scans, digital pathology slides, and genomic analyses
▪The I3LUNG machine learning and deep learning clinical and blood-only models achieved area under the curve values up to 0.77 in the independent test set

Subtopics

AI in healthcare2 AI1 AI interpretability1 AI research & benchmarks1 Cancer treatment1 Multimodal models1 OpenAI1 Public healthcare1 Science1

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