Stanford researchers genetically engineered mice without cortex or hippocampus and successfully replaced those regions with human brain organoids, creating a new platform for studying neuropsychiatric diseases including frontotemporal dementia and autism.
UC San Diego researchers demonstrated that a key cellular enzyme can accurately read an eight-letter genetic alphabet, doubling the four DNA letters used by all known life on Earth, with potential applications in synthetic biology and medicine.
Tim Andrews, a 66-year-old New Hampshire man with kidney failure, survived a record 271 days with a genetically modified pig kidney before receiving a human donor transplant. The case represents the first reported example of a pig kidney successfully serving as a bridge to human transplantation.
Researchers at USC have engineered a genetic tool that addresses a major obstacle in cancer immunotherapy by targeting the physical softness of solid tumors, potentially enabling CAR-T cell therapy to work against cancers it previously couldn't treat effectively.
Texas-based biotech company Colossal Biosciences has announced a de-extinction project to bring back the bluebuck, an African antelope species that went extinct approximately 226 years ago. The company plans to use genetic technology to resurrect the elegant species that was last seen alive around 1800.
