Intramuscular (depot) stories

Oct 28, 2026

WHO releases target regimen profiles for long-acting injectable tuberculosis treatments

The World Health Organization has published target regimen profiles for long-acting injectables (LAIs) for tuberculosis prevention and treatment, aiming to address adherence challenges associated with current daily oral regimens that must be taken over months.

Oct 28, 20261 source

Top claims

▪The World Health Organization target regimen profile for tuberculosis preventive treatment aims for a full treatment course administered as a single injection during one clinical encounter.
▪The World Health Organization defined minimal requirements as baseline criteria products must meet to be worth pursuing, and optimal requirements as desirable yet realistically achievable target specifications.
▪The World Health Organization's Target Regimen Profiles are intended to inform pharmaceutical companies, academia, research institutions, product development partners, affected communities, civil society, and donors early in product development.

Subtopics

Drug development1 Global health1 Infectious Disease and Outbreaks1 Injectable drug delivery devices1 Medication adherence1 Preventive medicine1 Public health policy1

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