New research published in Neurology Open Access finds that maintaining normal blood pressure, avoiding type 2 diabetes, and not smoking between ages 45-68 is associated with nearly 13 more years of dementia-free life after age 55 compared to those with all three risk factors.
Researchers have overturned longstanding scientific dogma by discovering that beginning around age 50, the brain's memory center loses its longtime resident immune cells (microglia) and replaces them with more inflammatory immune cells derived from peripheral blood stem cells. This previously unrecognized migration may help explain how normal aging sets the stage for Alzheimer's disease and dementia.
Researchers have overturned long-held scientific understanding by discovering that aging human brains undergo a massive influx of peripheral blood-derived immune cells starting around age 50, replacing resident microglia with more inflammatory cells. This shift may help explain how normal aging sets the stage for Alzheimer's disease and dementia.
Researchers have developed a novel artificial intelligence model that analyzes data from routine polysomnography sleep studies to identify patients' long-term health risks, including cognitive decline. The study was published in Nature Communications.
Scientists have discovered that blocking the Axl receptor may offer a novel approach to promoting bone formation, potentially providing a new treatment avenue for osteoporosis, a common age-related disease affecting millions worldwide.
The LiBBY clinical trial found that a combination of CBD and THC rapidly and significantly reduced agitation in hospice-eligible dementia patients, with nearly 90% of participants showing behavioral improvement in the nationwide study.
The U.S. Food and Drug Administration has approved LYTENAVA (bevacizumab-vikg) for treating neovascular age-related macular degeneration (wet AMD), marking the first FDA-approved ophthalmic formulation of bevacizumab after 20 years of off-label use. The approval comes on Outlook Therapeutics' fourth regulatory attempt, though the company faces cash constraints as it enters commercialization.
Scientists at Kyushu University in Japan have identified a sulfur-based compound called LASSS that protects and enhances a key muscle-repair protein called HGF, potentially offering a way to combat the muscle deterioration that occurs with aging. The compound appears to shield the protein from age-related chemical damage and more than double its strength.
The release of the 2025-2030 Dietary Guidelines for Americans has triggered scientific debate, with experts questioning whether current protein intake recommendations are sufficient for healthy aging and whether guidelines adequately address the needs of middle-aged and older adults.
The World Health Organization has issued updated global guidelines on reducing cognitive decline and dementia risk, stating that up to 45% of dementia cases may be preventable or delayed by addressing modifiable risk factors throughout life.
Preliminary official data shows at least 3,700 excess deaths across Western Europe following a severe late-June heatwave, with older populations particularly affected. The crisis has triggered political fallout in France, where the prime minister faces a no-confidence vote.
Lawsuits over vision loss risks from Saxenda (liraglutide) emerge as Medicare begins covering GLP-1 medications for seniors over 65, raising questions about proper usage and safety in older populations.
President Donald Trump, 79, underwent a medical examination at Walter Reed on Tuesday, his six-month physical that put his health under renewed public scrutiny amid ongoing concerns about his age and stamina. Trump declared afterward that everything checked out perfectly.
Frequent, long, or early-day naps in older adults are linked to higher mortality risk and may signal underlying conditions like cardiovascular disease, neurodegeneration, or sleep disorders, suggesting daytime sleep patterns could serve as an early warning sign of declining health.
Scientists at the Buck Institute and UC San Francisco discovered that APOE4, the most common genetic risk factor for Alzheimer's disease, causes bone quality deterioration in women, revealing an unexpected connection between neurological and skeletal health.
An experimental drug designed to silence a gene strongly linked to Parkinson's disease showed encouraging effects in reducing the target protein by up to 60% in a first-in-human clinical trial published in Nature Medicine.
Research from the University of Oulu suggests that large variations in bedtime during midlife may double the risk of cardiovascular events, highlighting the importance of consistent sleep schedules for heart health.
The UK government published its first national guidance on screen time for children, recommending no screen time for children under two (except video calls) and a maximum of one hour daily for ages two to five.
Medical professionals and neuroscientists are highlighting evidence-based strategies for maintaining brain health, including mental challenges, physical exercise, social engagement, and quality sleep. Research shows the brain begins shrinking around age 40, losing approximately 5% of volume per decade, making preventive habits increasingly important.
