Longevity & aging stories

Sep 7, 2026

AI-designed drug shows promise in reversing biological aging markers in clinical trial

Insilico Medicine announced that rentosertib, an experimental lung disease drug developed using artificial intelligence, demonstrated the ability to reduce biological age markers in a 42-patient trial. Six independently built aging clocks all showed patients on the drug appeared biologically younger, according to a study conducted with researchers from Harvard Medical School, Stanford University, and The Broad Institute.

Sep 7, 20264 sources

AI-discovered drug shows promise in reversing biological aging markers

Rentosertib, an experimental lung disease drug developed using artificial intelligence, demonstrated the ability to reverse biological signs of aging in a study, according to its developer, suggesting broader potential applications beyond its original target condition.

Sep 7, 20262 sources

Aug 3, 2026

APOE2 gene protects brain from Alzheimer's by reducing DNA damage

Research shows the longevity-linked APOE2 gene protects brain cells by reducing DNA damage and helping neurons recover from stress, potentially opening new treatment paths for Alzheimer's disease.

Aug 3, 20261 source

Aug 1, 2026

Eating less protein may slow aging and improve metabolism, major review finds

A comprehensive review of over 350 studies suggests that consuming less protein than currently popular may improve metabolism, reduce inflammation, and potentially slow aging processes.

Aug 1, 20261 source

Jul 30, 2026

Tech Entrepreneur Bryan Johnson Questions His Extreme Anti-Aging Regimen

Bryan Johnson, the US tech entrepreneur known for his extreme longevity experiments, publicly expressed doubts about his life mission in a social media post, suggesting he may have taken his anti-aging efforts too far.

Jul 30, 20261 source

Jul 24, 2026

Japanese Researchers Discover Sulfur Compound That May Slow Age-Related Muscle Loss

Scientists at Kyushu University in Japan have identified a sulfur-based compound called LASSS that protects and enhances a key muscle-repair protein called HGF, potentially offering a way to combat the muscle deterioration that occurs with aging. The compound appears to shield the protein from age-related chemical damage and more than double its strength.

Jul 24, 20267 sources

Jul 23, 2026

New U.S. Dietary Guidelines Spark Debate Over Protein Intake Recommendations for Aging Adults

The release of the 2025-2030 Dietary Guidelines for Americans has triggered scientific debate, with experts questioning whether current protein intake recommendations are sufficient for healthy aging and whether guidelines adequately address the needs of middle-aged and older adults.

Jul 23, 20264 sources

Jul 22, 2026

Biohacker Bryan Johnson Claims to Have Created Stem Cell Clone to Grow Replacement Organs

Tech entrepreneur and anti-aging advocate Bryan Johnson announced he has created what he describes as a 'newborn' version of himself using stem cells, with the goal of growing replacement organs after being diagnosed with autoimmune gastritis. The controversial experiment represents his latest effort in his 'Don't Die' longevity campaign.

Jul 22, 20263 sources

Jul 14, 2026

Semaglutide may slow biological aging in adults with HIV

Researchers found that semaglutide, the active ingredient in Ozempic and Wegovy, slowed biological aging markers in adults with HIV, marking the first clinical evidence that the drug may influence human aging beyond its metabolic effects.

Jul 14, 20261 source

Jul 7, 2026

Biohacker Bryan Johnson diagnosed with autoimmune gastritis amid quest to extend lifespan

Tech entrepreneur Bryan Johnson, who spends $2 million annually on anti-aging treatments in his quest to 'defeat death,' revealed he has been diagnosed with autoimmune gastritis, an incurable condition causing his stomach to 'eat itself.'

Jul 7, 20269 sources

Jun 9, 2026

First human receives cellular reprogramming therapy in landmark anti-aging clinical trial

The first participant has been treated in a groundbreaking clinical trial testing cellular reprogramming technology designed to rejuvenate aging cells. This marks the first time such reverse-aging therapy has been administered to a human.

Jun 9, 20262 sources

Jun 2, 2026

NewLimit Raises $435 Million Series C Ahead of First Clinical Trial for Longevity Medicine

Longevity-focused biotech startup NewLimit announced a $435 million Series C funding round as it prepares to launch its first clinical trial of a liver medicine, marking one of the largest recent raises in the longevity space.

Jun 2, 20261 source

May 22, 2026

Longevity Startup Retro Biosciences Raises Funding at $1.8 Billion Valuation

Retro Biosciences, the longevity startup backed by OpenAI CEO Sam Altman, announced it has raised additional funding at a $1.8 billion valuation, marking significant investor confidence in the anti-aging research space.

May 22, 20261 source

Apr 27, 2026

UK Healthy Life Expectancy Falls by Two Years Over Past Decade

The United Kingdom has seen a two-year decline in healthy life expectancy over the past decade, with poor housing, obesity, and deprivation cited as underlying causes.

Apr 27, 20261 source

Apr 21, 2026

Frequent Daytime Napping Linked to Early Signs of Health Decline in Older Adults

Frequent, long, or early-day naps in older adults are linked to higher mortality risk and may signal underlying conditions like cardiovascular disease, neurodegeneration, or sleep disorders, suggesting daytime sleep patterns could serve as an early warning sign of declining health.

Apr 21, 20264 sources

Apr 15, 2026

Loneliness Associated with Higher Risk of Degenerative Heart Valve Disease

Adults who reported feeling lonely had a higher risk of developing degenerative heart valve disease, even after accounting for traditional heart disease risk factors and genetics, according to new research.

Apr 15, 20261 source

Apr 13, 2026

Injectable Therapy Shows Promise to Reverse Osteoarthritis Within Weeks

Research team from University of Colorado Boulder, CU Anschutz, and Colorado State University developed new therapies that prompt aging or damaged joints to regenerate, potentially reversing osteoarthritis in a matter of weeks.

Apr 13, 20261 source

Apr 11, 2026

Experimental Parkinson's Drug Reduces Disease-Linked Protein by Up to 60% in First Human Trial

An experimental drug designed to silence a gene strongly linked to Parkinson's disease showed encouraging effects in reducing the target protein by up to 60% in a first-in-human clinical trial published in Nature Medicine.

Apr 11, 20261 source

Apr 8, 2026

23andMe Identifies Genetic Variants Predicting GLP-1 Drug Response and Side Effects

Research from 23andMe found that changes in two genes appear to help predict whether patients will lose substantial weight on GLP-1 drugs and whether they will experience nausea or vomiting.

Apr 8, 20261 source

Apr 5, 2026

Study Links Irregular Bedtime in Midlife to Doubled Risk of Cardiovascular Disease

Research from the University of Oulu suggests that large variations in bedtime during midlife may double the risk of cardiovascular events, highlighting the importance of consistent sleep schedules for heart health.

Apr 5, 20261 source

Apr 4, 2026

Small Molecule Drug Candidate Shows Promise for Rare Kidney Stone Disease with No Current Treatment

Scientists at the Buck Institute for Research on Aging demonstrated that an orally administered small molecule, N-propargylglycine (N-PPG), can completely prevent the formation of calcium oxalate kidney stones in preclinical studies.

Apr 4, 20261 source