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Apr 21, 2026

CAR-T Therapy Shows Promise in Preventing Multiple Myeloma in High-Risk Patients

Early trial results presented at AACR show CAR-T cell therapy may prevent smoldering multiple myeloma from progressing to active disease in high-risk patients, representing a potential preventive approach to cancer treatment.

Apr 21, 2026·2 sources

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Top claims

▪Darzalex is currently the only approved therapy for high risk smoldering myeloma
▪Many patients on Darzalex for high risk smoldering myeloma still progress to active multiple myeloma within five years
▪Patients on Darzalex for high risk smoldering myeloma can remain on treatment for years without achieving deep molecular responses

Subtopics

CAR T-cell therapy1 Clinical trials1 Drug Approval and Clinical Trials1 Immunotherapy1

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