Selective blockade of microRNA-31-5p−calcitonin receptor interaction reverses established atrial fibrosis and atrial arrhythmia burden - Nature Cardiovascular Research

Blocking microRNA-31-5p interaction reverses heart scarring and atrial fibrillation in study

Researchers at Baylor College of Medicine and University of Oxford found that blocking a specific molecular interaction between microRNA-31-5p and calcitonin receptor reduced atrial fibrosis and abnormal heart rhythms in mouse models and human cells, offering a potential RNA-based therapeutic strategy for atrial fibrillation.