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Biomedical research stories

Aug 12, 2026

Scientists develop genetic tool to make soft tumors vulnerable to CAR-T cell therapy

Researchers at USC have engineered a genetic tool that addresses a major obstacle in cancer immunotherapy by targeting the physical softness of solid tumors, potentially enabling CAR-T cell therapy to work against cancers it previously couldn't treat effectively.

Aug 12, 2026·2 sources
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Aug 6, 2026

Scientists Map Genetic Organization in Tonsil Cells, Revealing New Insights into Immune Function

Researchers have created a detailed map of how approximately 2 meters of genetic material organizes itself within tonsil cell nuclei, providing new understanding of how genes are accessed and used in immune responses.

Aug 6, 2026·1 source
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Jul 13, 2026

Universities, Research Groups, and California Attorney General Challenge Trump Administration's Proposed Federal Grant Rule

Top U.S. universities, scientific research advocates, patient groups, and California Attorney General Rob Bonta are urging the Trump administration to withdraw a proposed rule that would give the White House broad authority over more than $1 trillion in annual federal grant funding, warning it would politicize the grant process and undermine biomedical research.

Jul 13, 2026·3 sources
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Top claims

  • ▪CAR-T cells struggle to physically grab and penetrate softer, gelatinous cancer cells compared to stiffer cancer cells, reducing their therapeutic efficacy.
  • ▪The SHIFTERS system requires two keys for activation: the biological key of low oxygen (hypoxia) within the tumor and the physical key of focused ultrasound applied by a physician.
  • ▪While CAR-T cell therapy has produced remarkable results against blood cancers, its success has largely stopped at solid tumors of the brain, liver, lung, breast, and pancreas.

People involved

Rob Bonta

Subtopics

Cancer immunotherapy1CAR T-cell therapy1Gene expression1Genetic engineering1Trump administration1U.S. policy & law1

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