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Ultragenyx to lay off 20% of employees, scrap a Wilson disease gene therapy

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Ultragenyx to cut 20% of workforce after Wilson disease gene therapy failure

Ultragenyx Therapeutics announced plans to lay off approximately 20% of its employees and discontinue development of its Wilson disease gene therapy GTX-102 following a major setback in Angelman syndrome trials.

Nov 3, 2026·2 sourcesNovo NordiskGene therapyPharmaceutical IndustryGenetic diseasesCorporate layoffsAngelman syndromeCorporate restructuringEli Lilly
Ultragenyx to cut 20% of workforce after Wilson disease gene therapy failure
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STAT News

Ultragenyx cuts staff after another study fails