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Eli Lilly stories

Sep 30, 2026

Eli Lilly's amylin-Zepbound combination shows record 23% weight loss in diabetes trial

Eli Lilly reported that its experimental combination of amylin drug eloraTZP with Zepbound (tirzepatide) achieved up to 23% weight loss in patients with type 2 diabetes and obesity, outperforming Zepbound alone and representing the highest weight loss seen in similar studies to date.

Sep 30, 2026·6 sources
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Sep 29, 2026

Eli Lilly's retatrutide helps diabetes patients lose up to 21% body weight in late-stage trial

Eli Lilly reported that its experimental triple-agonist drug retatrutide helped adults with type 2 diabetes and obesity lose an average of nearly 21% of their body weight in a late-stage clinical trial, with more than half of patients dropping below the obesity threshold.

Sep 29, 2026·3 sources
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Sep 17, 2026

Novo Nordisk signs up to $1.4B partnership with Orbis Medicines for cardiometabolic drugs

Novo Nordisk agreed to a partnership worth up to $1.4 billion with Lilly-backed Orbis Medicines to develop macrocycle pills for heart and metabolic diseases, marking Orbis' first major pharma deal.

Sep 17, 2026·2 sources
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Aug 24, 2026

FDA clears Roche and Eli Lilly's blood test for Alzheimer's disease detection

The FDA has cleared a blood test developed by Roche and Eli Lilly to help identify signs of Alzheimer's disease in people aged 55 and older with cognitive decline.

Aug 24, 2026·3 sources
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Aug 12, 2026

Eli Lilly escalates legal fight against black market for experimental weight-loss drug retatrutide

Eli Lilly is stepping up legal action against a booming black market for retatrutide, an experimental weight-loss drug the company is counting on to expand its franchise beyond approved medications like Zepbound.

Aug 12, 2026·2 sources
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Jul 23, 2026

Eli Lilly's retatrutide shows positive Phase 3 results, plans Q1 2027 FDA application

Eli Lilly announced positive results from two additional Phase 3 trials of its experimental obesity drug retatrutide (a 'triple-G' GLP-1 receptor agonist), showing it did not increase overall heart risk. The company plans to submit an FDA application in Q1 2027.

Jul 23, 2026·3 sources
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Jul 15, 2026

Eli Lilly nears deal to acquire psychedelic drugmaker AtaiBeckley

Eli Lilly is in advanced talks to acquire AtaiBeckley, a psychedelic medicine company, with a deal potentially announced this week. The acquisition underscores growing interest from major pharmaceutical companies in psychedelic therapies.

Jul 15, 2026·2 sources
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Jul 14, 2026

Study finds frailty risks with GLP-1 drugs in older adults

A large study found potential signs of frailty in older adults taking Eli Lilly's Zepbound may signal relatively high risks for adverse outcomes, raising concerns about GLP-1 obesity drug use in elderly populations.

Jul 14, 2026·1 source
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Jun 29, 2026

FDA Selects Eli Lilly and Regeneron for Pilot Program to Accelerate Manufacturing Facility Reviews

The FDA selected seven companies including Eli Lilly and Regeneron for a pilot program designed to speed up reviews of new domestic pharmaceutical manufacturing facilities, aiming to strengthen U.S. drug supply chains.

Jun 29, 2026·2 sources
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Jun 23, 2026

Eli Lilly Grants Compassionate Use Access to Experimental Obesity Drug Retatrutide for Single Patient

Eli Lilly provided its experimental 'triple-G' weight loss drug retatrutide to a 79-year-old patient through the FDA's compassionate use program, marking an extremely rare instance of pre-approval access to an obesity medication.

Jun 23, 2026·2 sources
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May 28, 2026

CVS Health Restores Coverage of Eli Lilly's Zepbound and Adds New Obesity Pill to Drug Plans

CVS Health announced it will add Eli Lilly's weight-loss drug Zepbound back to some of its drug lists as an additional preferred option and begin coverage for the drugmaker's newly approved obesity pill, Forza.

May 28, 2026·2 sources
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May 26, 2026

Eli Lilly Acquires Three Vaccine Developers, Expanding Infectious Disease Portfolio

Eli Lilly is acquiring three small vaccine developers, marking a significant expansion into infectious disease vaccines and providing a boost to the vaccine development field.

May 26, 2026·1 source
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May 25, 2026

Eli Lilly's Gene-Editing Therapy Reduces Cholesterol by 62% in Early Clinical Trial

Eli Lilly reported that a high dose of its gene-editing therapy from Verve Therapeutics reduced cholesterol levels by 62% in participants in an early-stage clinical trial, representing a significant advance in gene-editing treatments for cardiovascular disease.

May 25, 2026·1 source
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May 18, 2026

Trump Invested in Eli Lilly Stock as Administration Boosted Obesity Drug Policies

New ethics disclosures reveal President Trump purchased stock in Eli Lilly and an injectable device manufacturer while his health agencies implemented policies benefiting these companies' obesity drug products.

May 18, 2026·1 source
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May 5, 2026

French Regulator Fines Novo Nordisk and Eli Lilly Over Weight Loss Drug Ad Campaigns

France's medicines regulator has imposed fines on Novo Nordisk and Eli Lilly for their weight loss drug advertising campaigns, marking a significant regulatory action against the pharmaceutical giants' marketing practices.

May 5, 2026·1 source
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May 3, 2026

Eli Lilly Raises 2026 Guidance as GLP-1 Drug Demand Surges in Q1

Eli Lilly reported strong Q1 2026 financial results driven by massive growth in Mounjaro and Zepbound sales, leading the company to raise its full-year guidance amid surging demand for GLP-1 medications.

May 3, 2026·1 source
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May 1, 2026

FDA Moves to Remove GLP-1 Weight Loss Drugs from Compounding List

FDA announced plans to exclude semaglutide, tirzepatide, and liraglutide from its 503B compounding list, citing no shortage of GLP-1 drugs from Novo Nordisk and Eli Lilly.

May 1, 2026·1 source
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Apr 28, 2026

Eli Lilly Partners with AI Startup Profluent to Develop Next-Generation Gene Editors Beyond CRISPR

Eli Lilly has entered a deal with AI startup Profluent to develop AI-designed enzymes capable of inserting entire genes, moving beyond traditional CRISPR technology. The partnership aims to reshape genetic medicine by using artificial intelligence to create novel gene editing tools.

Apr 28, 2026·1 source
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Apr 16, 2026

FDA Requests Additional Liver Injury Data on Eli Lilly Obesity Pill Foundayo

The FDA has asked Eli Lilly for more data on liver injury linked to its newly approved obesity pill Foundayo.

Apr 16, 2026·1 source
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Top claims

  • ▪Eli Lilly's EloraTZP combination approach targets three nutrient-stimulated hormone pathways—GLP-1, GIP, and amylin—to lightly engage multiple natural satiety systems rather than heavily targeting a single hormone system
  • ▪EloraTZP combines eloralintide, an experimental selective amylin receptor agonist mimicking the pancreatic hormone amylin that signals fullness, with tirzepatide, the active ingredient in Eli Lilly's Zepbound and Mounjaro that targets GLP-1 and GIP gut hormones
  • ▪Eli Lilly plans to initiate Phase 3 clinical trials for the EloraTZP combination treatment by the end of 2026, which will include adjusted dosing schedules to improve tolerability

People involved

Donald Trump

Subtopics

Pharma15GLP-1 medications9Drug Approval and Clinical Trials8Lifestyle, Wellness and Nutrition8Weight management7Clinical trials5Zepbound5Obesity treatment4Retatrutide4Healthcare Policy3Novo Nordisk3Pharmaceutical Industry3Drug development2Mental health2Public healthcare2US health policy & drug pricing2Age related cognitive decline1AI for developers1Alzheimer’s & dementia1Bioethicists of life extension1Biomarkers & bloodwork testing1Cardiovascular training1Cholesterol management1Corporate earnings1

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