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GB2Ab Antibody Reverses Weight, Muscle Loss in Cancer Mice

ChosunView source article

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KAIST researchers develop GB2Ab antibody to treat cancer cachexia in mice

A research team at KAIST has developed GB2Ab, a therapeutic antibody candidate that blocks signals responsible for appetite suppression, weight loss, and muscle wasting in cancer cachexia. The antibody successfully reversed weight and muscle loss in mouse models.

Oct 29, 2026·2 sourcesCancer and Cancer TreatmentCancer treatmentCancer researchCancer & OncologyDrug developmentBiomedical researchBiotech innovation
KAIST researchers develop GB2Ab antibody to treat cancer cachexia in mice
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Medicalxpress

Antibody candidate could help preserve appetite and muscle strength in patients with cancer