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Dermatology stories

Oct 2, 2026

Biogen's daxdilimab reduces disease activity in moderate-to-severe discoid lupus trial

Biogen's experimental monoclonal antibody daxdilimab demonstrated significant reduction in disease activity with favorable safety profile in Phase 2 trial for patients with moderate-to-severe discoid lupus erythematosus.

Oct 2, 2026·2 sources
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Sep 30, 2026

Merck's experimental skin disease drug succeeds in mid-stage study

Merck reported positive mid-stage trial results for an experimental drug targeting a painful skin disease, marking progress in the company's dermatology pipeline.

Sep 30, 2026·2 sources
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Aug 18, 2026

Leo Pharma acquires worldwide rights to dersimelagon for up to $435M

Danish drugmaker Leo Pharma agreed to acquire worldwide rights to dersimelagon, a late-stage drug candidate for two rare genetic skin diseases, from Tanabe Pharma for up to $435 million in upfront and milestone payments.

Aug 18, 2026·2 sources
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Top claims

  • ▪The mid-stage trial of litifilimab enrolled 93 adults whose skin symptoms had not responded to standard antimalarial medicines
  • ▪No serious adverse events or deaths were reported in the phase 2 trial of daxdilimab for moderate-to-severe discoid lupus erythematosus, and treatment-related adverse events occurred in 58.3% of the low-dose, 56.5% of the high-dose, and 60% of the placebo cohorts
  • ▪Using placebo controls in trials for treatment-refractory discoid lupus is ethically acceptable

Topics

PharmaGenetic disorders

Related entities

Autoimmune diseaseMerckRare Disease