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Lycia Therapeutics targets $938 million valuation in US IPO
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Lycia Therapeutics targets $938 million valuation in US IPO

Oct 20, 2026

Biotechnology company Lycia Therapeutics, founded in 2019 by Nobel laureate Carolyn Bertozzi, is targeting a valuation of up to $937.7 million in a U.S. IPO to raise $264.6 million on the Nasdaq under symbol LYCA. The South San Francisco firm joins a wave of fall healthcare listings, including City Therapeutics' $230 million upsized offering and Iambic Therapeutics, as investors selectively back biotech developers.

Lycia Therapeutics initial public offering terms

  • ▪Lycia Therapeutics is targeting a market valuation of up to $937.7 million in its U.S. initial public offering announced on October 20, 2026.
  • ▪Lycia Therapeutics is seeking to raise up to $264.6 million in its U.S. initial public offering by offering 14.7 million common shares.
  • ▪Lycia Therapeutics set the price range for its initial public offering shares between $16 and $18 per share.

Lycia Therapeutics listing and bookrunners

  • ▪Lycia Therapeutics plans to list its common stock on the Nasdaq Global Market under the ticker symbol LYCA.
  • ▪Jefferies, TD Cowen, Evercore ISI, and Guggenheim Securities are serving as joint book-running managers for the Lycia Therapeutics offering.

Lycia Therapeutics funding and shareholders

  • ▪Lycia Therapeutics has raised approximately $266.6 million from life sciences investors since its founding in 2019.
  • ▪Major shareholders in Lycia Therapeutics include Versant Ventures, Venrock Healthcare, Redmile Group, RTW Investments, Janus Henderson, and Blue Owl.

Lycia Therapeutics overview and pipeline

  • ▪Nobel Prize winner Carolyn Bertozzi co-founded South San Francisco-based biotechnology firm Lycia Therapeutics.
  • ▪South San Francisco-based Lycia Therapeutics was founded in 2019 to develop targeted therapeutics designed to treat autoimmune, inflammatory, and allergic diseases.
  • ▪Lycia Therapeutics is advancing its lead experimental drug candidate LCA-0061 in an early-stage clinical trial for patients with food allergies.

Other recent biotech initial public offering activity

  • ▪Aspen Neuroscience and Bambusa Therapeutics filed registration statements for U.S. initial public offerings in early October 2026.
  • ▪Drug developers City Therapeutics and Nvidia-backed Iambic Therapeutics completed initial public offerings in New York in October 2026.

City Therapeutics initial public offering

  • ▪City Therapeutics common stock began trading on the Nasdaq Global Market under ticker symbol CTY on October 16, 2026.
  • ▪City Therapeutics closed an upsized initial public offering of 12,777,777 common shares at $18.00 per share on October 19, 2026, raising $230.0 million in gross proceeds.

3 sources

Biospace
City Therapeutics Announces Closing of $230.0 Million Upsized Initial Public Offering, Including Full Exercise of Underwriters’ Option to Purchase Additional Shares
View source article
Cryptobriefing
Elice's disappointing IPO sparks debate on AI valuations
View source article
Reuters
Drug developer Lycia Therapeutics targets $938 million valuation in US IPO | Reuters
View source article

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Drug development