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FDA Approves Rocket Pharmaceuticals Gene Therapy for Rare Immune Disorder
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FDA Approves Rocket Pharmaceuticals Gene Therapy for Rare Immune Disorder

Mar 26, 2026

Novo Nordisk chairman Lars Rebien Sorensen faces investors on March 26, 2026 at the company's annual meeting for the first time since orchestrating a boardroom coup that ousted former CEO Lars Fruergaard Jorgensen in May 2025. Since the leadership change, Novo Nordisk shares have plunged 45% while competitor Eli Lilly briefly became the world's first $1 trillion drugmaker with market value growing by a fifth during the same period. The struggling Danish pharmaceutical company has cut Wegovy prices in South Africa twice since launching there in August 2025, with the lowest dose dropping 60% to $110 and the highest falling 27% to $221, as it battles Eli Lilly's market dominance. New CEO Mike Doustdar and Sorensen have had only months to remake Novo Nordisk into a more aggressive competitor after a failed acquisition attempt of a Pfizer obesity startup and a gloomy 2026 forecast that further rattled markets.

Novo Nordisk leadership crisis and investor concerns

  • ▪Novo Nordisk shares have fallen about 45% since Lars Rebien Sorensen intervened to oust former CEO Lars Fruergaard Jorgensen in May 2025
  • ▪Eli Lilly briefly became the world's first $1 trillion drugmaker between May 2025 and March 2026
  • ▪Novo Nordisk surprised the market in 2026 with a gloomy forecast that sent Novo Nordisk shares plunging
  • ▪Novo Nordisk chairman Lars Rebien Sorensen will face investors at Novo Nordisk's annual meeting on Thursday March 26, 2026 for the first time after his boardroom coup
  • ▪Novo Nordisk failed in an attempt to acquire an obesity startup from Pfizer in fall 2025
  • ▪Eli Lilly's market value grew by a fifth between May 2025 and March 2026

Wegovy pricing strategy in South Africa amid competition

  • ▪The highest dose of Wegovy in South Africa fell 27% to $221
  • ▪A 12% cut to the 1.7-milligram dose of Wegovy in South Africa awaits approval as of March 26, 2026
  • ▪Novo Nordisk reduced Wegovy prices in South Africa in December 2025
  • ▪The lowest injected dose of Wegovy in South Africa dropped 60% to $110
  • ▪Novo Nordisk is cutting South African prices of Wegovy for a second time since Wegovy launched in South Africa in August 2025
  • ▪Novo Nordisk launched Wegovy in South Africa in August 2025 when reference pricing was uncertain due to talks with the U.S. administration on its proposed most-favored nation policy
  • ▪Novo Nordisk submitted another Wegovy price reduction in South Africa on March 25, 2026

Perspective of Novo Nordisk investors

  • ▪Novo Nordisk's failed acquisition attempt of a Pfizer obesity startup in fall 2025 represents a missed opportunity to strengthen the company's competitive position
  • ▪Novo Nordisk investors have experienced approximately 45% share value decline since the May 2025 CEO ousting, contrasting sharply with Eli Lilly's market gains

Perspective of Eli Lilly

  • ▪Eli Lilly's achievement as the world's first $1 trillion drugmaker between May 2025 and March 2026 occurred during the same period Novo Nordisk lost 45% of its market value

Perspective of South African healthcare market stakeholders

  • ▪South African patients gained access to the lowest Wegovy dose at $110 after a 60% price reduction, making obesity treatment more affordable

3 sources

Statnews
STAT+: FDA approves Rocket gene therapy for rare immune disorder
View source article
Statnews
STAT+: Pharmalittle: We’re reading about an FDA OK for a rare disease drug, a grilling of the PTO chief, and more
View source article
Statnews
STAT+: Denali Therapeutics, Corcept Therapeutics win FDA approvals
View source article

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Related entities

Novo NordiskSouth AfricaEli Lilly

Related Projects

Pfizer

Topics

Rare DiseaseDrug Approval and Clinical TrialsPharma