A 10-year clinical trial presented at ASN Kidney Week 2026 by Dr. Nimrit Goraya found that dietary treatment with fruits and vegetables for metabolic acidosis in stage 3 chronic kidney disease outperforms standard sodium bicarbonate and usual care. Patients receiving fruits and vegetables had significantly lower rates of hospitalizations (14 vs 64), emergency visits (20 vs 88), and dialysis progression (4 vs 16) compared to usual care, without increasing overall healthcare costs.
Trial design and treatment groups
- ▪A 10-year clinical trial led by Dr. Nimrit Goraya evaluated 108 adults with stage 3 chronic kidney disease and metabolic acidosis randomized equally into fruits and vegetables, oral sodium bicarbonate, and usual care groups.
- ▪In a trial of 108 adults with stage 3 chronic kidney disease and metabolic acidosis, oral sodium bicarbonate treatment was prescribed to reduce dietary acid by half in 36 participants.
- ▪In a clinical trial presented at ASN Kidney Week 2026, dietary acid reduction using base-producing fruits and vegetables reduced dietary acid intake by half in 36 adults with stage 3 chronic kidney disease.
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