Trump Signs Executive Order to Accelerate Psychedelic Drug Reviews Including Controversial Ibogaine

Apr 19, 2026

President Donald Trump signed an executive order directing the FDA to expedite reviews of psychedelic drugs including ibogaine, a controversial substance derived from a West African plant that has been embraced by military veterans for treating post-traumatic stress. The order, signed at a Saturday Oval Office event attended by podcast host Joe Rogan and former Navy SEAL Marcus Luttrell, calls for at least $50 million in federal funding for state psychedelic programs and directs the FDA to issue national priority vouchers for three psychedelics this week. The move clears the way for the first-ever human trials of ibogaine in the United States, despite the drug remaining banned under federal law and previous research being stalled by concerns over potentially fatal heart problems. The initiative represents rare bipartisan support for psychedelic research, with Health Secretary Robert F. Kennedy Jr. having previously pledged to ease access to psychedelics for medical use.

Trump's Executive Order on Psychedelic Drug Reviews

▪Donald Trump's executive order calls on the federal government to relax restrictions on psychedelics for potential treatments.
▪United States President Donald Trump signed an executive order to speed up the review of psychedelic drugs including ibogaine.
▪Donald Trump joked about being open to taking psychedelics himself during the signing event.
▪Donald Trump signed the executive order on psychedelic drug reviews during a Saturday Oval Office event.

Joe Rogan's Advocacy for Ibogaine Treatment

▪Donald Trump texted Joe Rogan back asking if Rogan wanted FDA approval for ibogaine.
▪Joe Rogan has publicly questioned the Trump administration's war with Iran, saying it runs counter to Trump's campaign pledges.
▪Joe Rogan's endorsement helped boost Donald Trump ahead of the 2024 presidential election.
▪Joe Rogan is considered one of the most influential podcasters in the United States.
▪Joe Rogan previously texted information to Donald Trump about ibogaine.

FDA Actions and Federal Funding for Psychedelic Research

▪Health Secretary Robert F Kennedy Jr had previously pledged to ease access to psychedelics for medical use.
▪Increasing research into psychedelics has proven a rare issue with bipartisan support in the United States.
▪Donald Trump's executive order calls on the Department of Health and Human Services to direct at least $50 million to states that have enacted or are developing programs to advance psychedelic drugs for serious mental illness.
▪FDA Commissioner Marty Makary stated that national priority vouchers will allow certain drugs to be approved quickly if they are in line with national priorities.
▪Previous ibogaine research in the United States had been stalled by concerns over the drug potentially triggering fatal heart problems.
▪The FDA is taking steps to clear the way for the first-ever human trials of ibogaine in the United States.
▪Ibogaine and other psychedelics remain banned under the federal government's most restrictive category for illegal drugs in the United States.

Ibogaine's Origins and Use Among Military Veterans

▪Marcus Luttrell, a former Navy SEAL, was present at the Saturday executive order signing ceremony.
▪Marcus Luttrell's memoir about his time in Afghanistan, Lone Survivor, was made into a film.

Perspective of Joe Rogan and psychedelic advocates

▪Joe Rogan actively lobbied Donald Trump to pursue FDA approval for ibogaine through direct communication.

Perspective of FDA and medical safety regulators

▪Previous ibogaine research in the United States had been stalled by concerns over the drug potentially triggering fatal heart problems.
▪FDA Commissioner Marty Makary stated that national priority vouchers will allow certain drugs to be approved quickly if they are in line with national priorities.